Changes in Ovarian Stromal Function in Premenopausal Woman Undergoing Chemotherapy for Breast Cancer

Abstract

The objective of this pilot study is to identify if androgen levels are adversely affected by adjuvant chemotherapy for breast cancer and whether low androgen levels are correlated with the frequency and severity of fatigue, weight gain, psychological symptoms, vasomotor symptoms and libido. A longitudinal, descriptive design will be used with questionnaires completed and blood drawn from 20 pre menopausal women at 4 time periods: baseline(before treatment), mid-treatment, immediate post-treatment and 6 months later. Questionnaires include the Female Sexual Function Index, Greene Climacteric Scale, Profile of Mood States, Schwartz Fatigue Scale and a menaces diary.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2006
Accession Number
ADA462081

Entities

People

  • Anne E. Kearns
  • Charles L. Loprinzi
  • Debra L. Barton
  • Jeff A. Sloan
  • Marlene H. Frost

Organizations

  • Mayo Clinic

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Body Weight
  • Breast Cancer
  • Chemotherapy
  • Data Analysis
  • Department Of Defense
  • Drug Therapy
  • Hormones
  • Intervention
  • Neoplasms
  • Oncology
  • Pilot Studies
  • Quality Of Life
  • Societies

Readers

  • Molecular Biology and Genetics
  • Oncology and Biomarker-Based Cancer Detection.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.