Bacterial Degradation of DNT and TNT Mixtures
Abstract
The major objective of this research project was to develop bacterial strains with the ability to efficiently degrade mixtures of dinitrotoluene (DNT) isomers and expand that degradation capability to include TNT. Since most contaminated sites contain mixtures of nitroarene compounds, these strains would have the potential for use in the bioremediation of field sites. We have isolated strains that can degrade several nitroarene compounds, including nitrobenzene, 2-nitrotoluene (2NT) and 2,4- and 2,6-DNT. A clear understanding of the biochemistry, physiology, and molecular genetics of these pathways is a necessary prerequisite for pathway engineering. To this end, we characterized the pathways and enzymes involved, investigated regulation systems, and identified the inducing molecules.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 31, 2005
- Accession Number
- ADA462201
Entities
People
- Glenn R. Johnson
- Jim C. Spain
- Rebecca E. Parales
Organizations
- University of California, Davis