Molecular Epidemiology of Ovarian Cancer
Abstract
The aim of this Program is to study the association between epidemiologic risk factors, low-risk genes, and histologic and novel molecular subtypes of ovarian cancer. In December 2002, we received final approval from the Human Subject Research Review Board (HSRRB) to start recruitment at 13 of the proposed study sites and have since received approval to recruit at a further 2 sites. We have established a network of research nurses across the country and recruitment is now progressing well at 15 different sites. Recruitment of cases for the study began in January 2003 and control recruitment began in May 2003. Full population-based recruitment of cases ceased for women diagnosed after 30 June 2005 but collection of biospecimens and limited epidemiological data continued at key centres until June 2006. We have recruited a total of 1707 women with ovarian cancer (with an additional 296 women recruited since 1 July 2005 for the biospecimens extension) and 1073 control women. The recruitment, sample and data collection and processing systems have worked well and we are continuously monitoring our performance against our targets as outlined in the reports from Core Components A (Epidemiology) and B (Biospecimens).
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2006
- Accession Number
- ADA462587
Entities
People
- David Bowtell
Organizations
- University of Melbourne