Telomere Length as a Predictor of Aggressive Prostate Cancer

Abstract

We are evaluating whether men with shorter telomere length in prostate cancer tissue and in normal appearing prostate tissue adjacent to adenocarcinoma have a higher risk of aggressive prostate cancer than men with longer telomere length. Since the last progress report (Nov 2005) the tissue microarrays were assembled by our Harvard collaborators. At Hopkins, we completed staining of the tissue microarrays for telomere length and are in the processing of imaging the spots and estimating telomere length.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2006
Accession Number
ADA463411

Entities

People

  • Elizabeth A Platz

Organizations

  • Johns Hopkins University

Tags

DTIC Thesaurus Topics

  • Adenocarcinoma
  • Biological Staining And Labeling
  • Biomedical Research
  • Blood
  • Cancer
  • Carcinoma
  • Cells
  • Chromosome Structures
  • Diseases And Disorders
  • Epithelial Cells
  • Epithelium
  • Infection
  • Magnification
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Tissues

Readers

  • Mathematics or Statistics
  • Oncology and Biomarker-Based Cancer Detection.