Superoxide Dismutase and Transcription Factor sox9 as Mediators of Tumor Suppression by mac25 (IGFBP-rp1) in Prostate Cancer Cells

Abstract

The most significant conclusion that is going to be derived from the work on this proposal is the relationship of tumor cell contribution to the extra cellular environment and tumor growth. This was unexpected when we started this proposal and this work has not been completed. However, based on the findings generated in this DOD proposal Dr. Plymate has received a 5 yr NCI/NIH U54 Program Project to further develop these interactions.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2006
Accession Number
ADA463476

Entities

People

  • Stephen R Plymate

Organizations

  • University of Washington

Tags

DTIC Thesaurus Topics

  • Cancer
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Culture Media
  • Culture Techniques
  • Dna Microarrays
  • Enzyme Inhibitors
  • Epithelial Cells
  • Genetics
  • Health Services
  • Peptide Growth Factors
  • Proteins

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  • Immunology and Pathology
  • Molecular Biology and Genetics