Development of the Meharry Medical College Prostate Cancer Research Program

Abstract

African Americans (AA) are disproportionately affected by prostate cancer (PCa) for reasons including, biologic tumor differences, genetic predisposition, differential exposures, lack of access to prostate specific antigen (PSA) testing, inadequate access to health care, paucity of minority PCa investigators, and low accrual of AAs in clinical trials. We propose a research team at an HBCU to study the molecular, genetic, dietary, and body fat patterns in the pathogenesis of PCa disparity among AA and African men. There is substantial urology, oncology, epidemiology, nutrition and other expertise in both institutions, now developing this program at MMC, by training new and junior minority investigators, maintaining lasting partnership with mentors, and establish viable community network ties. One project will investigate health care seeking behavior of AA, another will investigate the role of lycopene in PCa risk, a third will look at genetic risk factors, and two studies will study the growth inhibitory effect of Thalidomide and other agents on PCa cell lines. The program has attracted graduate students, has identified, and is currently in the process of hiring a second post-doctoral fellow.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2006
Accession Number
ADA463484

Entities

People

  • Flora A. M. Ukoli

Organizations

  • Meharry Medical College

Tags

DTIC Thesaurus Topics

  • African Americans
  • Biological Sciences
  • Cancer
  • Cell Line
  • Clinical Trials
  • Education
  • Health
  • Health Care
  • Health Services
  • Medical Personnel
  • Neoplasms
  • Physicians
  • Prostate Cancer
  • Public Health
  • Risk Factors
  • Students
  • Training

Fields of Study

  • Medicine

Readers

  • Prostate Cancer Biology.
  • STEM Education
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology