Design and Development of Nanoscale Biomotor Power Units
Abstract
1. We have continued to refine our theoretical model for the design of a bacterial cell powered motor. 2. We have determined what types of surfaces bind motile bacterial cells. 3. We have monitored surface adhered bacterial cell motility using fluorescent dyes and found that cells remain alive and motile for more than 4 hours. 4. We have discovered that E. coli bacterial cells will not bind to surface dot features with a diameter of 1.2 micrometers or smaller. 5. We have designed and fabricated "holed' surfaces that bind motile bacterial cells in a "nose-on" fashion. 6. We have used DPN to attach bacterial cells to surfaces. 7. We have obtained and attached CheY deficient (Pseudomonas aeruginosa) "smooth swimming" bacterial cells to prefabricated micro-array surfaces. 8. We have generated an initial design and fabricated a prototype micro-scale biomotor. 9. We have "proof-of-concept" that motile bacterial cells can spin a device. Progress in the last four years has been excellent, and included the publication of three manuscripts (Small, Talanta and, Langmuir). We currently have at least two additional manuscripts in preparation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 21, 2007
- Accession Number
- ADA464307
Entities
People
- Richard C. Holz
Organizations
- Utah State University