Role of Caveolin-1 in Prostate Cancer Angiogenesis

Abstract

Overall we have made exceptional progress in the first year funding period of this project. Tasks 1-3 are on schedule and although as is often the case we have made some unanticipated and necessary adjustments (replacement of 178-2BMAK cells with RM-9 cells for Task 3) we are moving toward our stated goals. Importantly our data thus far are yielding important mechanistic insight into the angiogenic activities of prostate cancer cell derived secreted cav-1. In our view after we further define these mechanisms we will be able to take the next important step exploiting this new knowledge for prostate cancer diagnosis and therapy.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2006
Accession Number
ADA466161

Entities

People

  • Timothy C Thompson

Organizations

  • Baylor College of Medicine

Tags

DTIC Thesaurus Topics

  • Albumins
  • Angiogenesis
  • Biomedical Research
  • Blood
  • Cells
  • Chemistry
  • Culture Media
  • Diseases And Disorders
  • Endothelial Cells
  • Gene Expression
  • Molecules
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Proteins
  • Statistical Analysis
  • Tissues

Readers

  • Oncology (Cancer Research).
  • Prostate Cancer Biology.
  • Systems Analysis and Design