Efficacy of Calcium and Vitamin D Supplementation for the Prevention of Stress Fractures in Female Naval Recruits
Abstract
The goal is to determine if calcium and vitamin 0 supplementation can reduce the incidence of stress fracture by at least 50% in female Naval recruits during basic training. The secondary goal is to examine the potential mechanisms for increasing bone adaptation to intense mechanical loading. The Command Officers at the Great Lakes Naval Station stopped the study on xxx because we had recruited our originally targeted sample size. We recruited 5201 females who were randomly assigned to calcium 2000 mg and vitamin 0 800 l.U. per day or a control placebo group. The intervention and stress fracture monitoring continued through 8 weeks of basic training. We were not able to recruit the targeted number of subjects for the sub-study designed to determine changes in moment of inertia using peripheral quantitative computed tomography(pOCT). We enrolled 148 (out of a target 560) In the 3703 participants who completed the main study we found that calciumiD supplementation decreased the incidence of stress fracture by 27%(p=0.02). Furthermorn supplementation suggest that supplementation can compensate for a history of low physical activity.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2006
- Accession Number
- ADA466171
Entities
People
- Joan M. Lappe
Organizations
- Creighton University