Structural Studies on Toxins and Virulence Factors of Yersinia Pestis

Abstract

In this second annual report, we present our progress on two different areas, protein production and crystallization. We are working on expression and purification of Yop proteins and their complexes. We have made progress in purifying YopB; SycD complex. We are also purifying Yop B, D and E complex to understand the translocation machinery.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2005
Accession Number
ADA466704

Entities

People

  • Subramanyam Swaminathan

Organizations

  • Brookhaven National Laboratory

Tags

DTIC Thesaurus Topics

  • Biological Factors
  • Biological Toxins
  • Crystallization
  • Isothermal Processes
  • Production
  • Virulence

Fields of Study

  • Chemistry

Readers

  • Microbial Pathology
  • Molecular and Cellular Biochemistry