Experiments, Computation, and Modeling for Temperature Dependence of Absorption, Scattering, Reflection, Transmission, and Index of Refraction of Optical Radiation in Biological Tissues
Abstract
The objective of this research was to systematically measure the temperature dependence of optical properties of various bovine eye tissues at elevated temperatures (above body temperature) using different experimental and computational techniques. The temperature dependence of absorption and scattering coefficients of bovine ocular tissue in the temperature range of 24 to 40 degrees C at 980nm was measured. After computing diffuse reflectance and total transmittance, it was determined that any temperature dependence of the diffuse reflectance and total transmittance could not be discerned with the current setup in the temperature range of interest. The average diffuse reflectance and total transmittance values over all measured temperatures were input into the inverse adding doubling computer program. The resulting absorption coefficients were comparable to those reported by Sardar et al., but the scattering coefficients were not, perhaps due to some specular reflection inadvertently measured in the previous work. The rate of change of the refractive index with respect to temperature was performed at 632.8nm for bovine aqueous and vitreous humor in the temperature range of 37 to 41 degrees C. using the Mach-Zehnder interferometer setup. The measured refractive index with respect to temperature for bovine aqueous humor was comparable to that of water, while the measured value for bovine vitreous humor was slightly less than the value for water. These values are necessary for accurately modeling thermal lensing and hence light propagation in the eye.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 2006
- Accession Number
- ADA466743
Entities
People
- Dhiraj K. Sardar
- Raylon M. Yow
- Robert J. Thomas
Organizations
- University of Texas at Austin