Exploring Early Detection Methods: Using the Intraductal Approach to Predict Breast Cancer
Abstract
Nipple aspiration ductal lavage and ductography are methods of obtaining breast fluids from women who are neither pregnant or lactating. Breast cells in these fluids can be classified as either normal or as showing various abnormalities including hyperplasia atypical hyperplasia and cancer. In previous follow-up studies of women who participated in breast fluid and tissue studies it was shown that women with proliferative cytology (hyperplasia or atypical hyperplasia) were significantly more likely to develop breast cancer than women with normal cytologic findings in breast fluids or than women from whom fluid could not be obtained. (Fabian et al. 2000; Wrensch et al. 2001) This study followed an additional cohort of women from Santa Barbara CA that had fluids drawn between 1970-1990. Statistical methods of association were used to determine if women with abnormal ctyologic findings developed breast cancer at a higher rate than women with normal cytologic findings or women from whom fluid could not be obtained. Overall 10% (93) of the 946 women developed breast cancer during the follow-up period.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 2006
- Accession Number
- ADA467814
Entities
People
- Kimberly Baltzell
- Marylin Dodd
Organizations
- University of California, San Francisco