Vasculature-Specific Adenovirus Vectors for Gene Therapy of Prostate Cancer

Abstract

In Year 3 of the project we have completed Task 3 and began the work in Task 4 (as per approved Statement of Work). As a result, we have rescued, propagated and characterized a panel of adenovirus vectors that are now ready for the in vivo studies that will conclude the project. To facilitate the monitoring of tumor growth and regression in these studies, we have also developed cell lines expressing dual reporters that are suitable for non-invasive in vivo imaging of tumors.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2007
Accession Number
ADA468057

Entities

People

  • Victor Krasnykh

Organizations

  • The University of Texas MD Anderson Cancer Center

Tags

DTIC Thesaurus Topics

  • Adenoviruses
  • Biomedical Research
  • Blood Vessels
  • Cell Line
  • Cells
  • Clones
  • Gene Delivery
  • Gene Therapy
  • Genetic Engineering
  • Monitoring
  • Mouth Diseases
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Targeting
  • Therapy
  • Viruses

Readers

  • Molecular Genetics
  • Oncology (Cancer Research).

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech