Characterization Of Commonly Encountered Explosives Using Highfield Asymmetric Waveform Ion Mobility Spectrometry Coupled With Mass Spectrometry
Abstract
The goal of this research was to characterize explosive compounds using high-field asymmetric waveform ion mobility spectrometry (FAIMS) as an ion separation device interface to a mass spectrometer (MS). FAIMS is a relatively recently developed technology that is promising adding a dimension of separation. This method was employed in such a way as to be conducive to possible future development of field instruments (e.g., use of atmospheric pressure chemical ionization (APCI)). In addition, several experiments were conducted with the application of this method, mainly dealing with optimization of the instrument parameters. These experiments led to the development of a new method: high-resolution FAIMS. An ion mobility spectrometer was used as a desolvation and ion focusing device to drastically improve FAIMS resolution. This allowed for the separation of mixtures that otherwise could not have been separated. The resolution was high enough that isomers of the same explosive were successfully resolved. This can be beneficial to forensics studies.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2007
- Accession Number
- ADA468495
Entities
People
- Jared J. Boock
Organizations
- University of Florida