Development of an Automated Modality-Independent Elastographic Image Analysis System for Tumor Screening

Abstract

The objective of this project is to further develop modality-independent elastography as a system that is able to reproducibly detect regions of increased stiffness within the breast based on pre- and post- compression input images of the anatomy. As stated in the proposal, the original specific aims are concerned with enhancement of the method, investigation of texture and statistical analyses for evaluating the success of the method, and engineering of a device that can generate proper forces on mock setups within current available clinical imaging systems. To date, progress on each of these aims has been made in handling increased computational complexity, developing and testing metrics for the evaluation of reconstructions, and the fabrication of a compression chamber tested on a tissue-like polymer phantom.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2007
Accession Number
ADA468508

Entities

People

  • Jao J. Ou
  • Michael I. Miga

Organizations

  • Vanderbilt University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Breast Cancer
  • Diagnostic Imaging
  • Elastic Properties
  • Engineering
  • Health Services
  • Image Processing
  • Materials Processing
  • Mechanical Properties
  • Mechanical Working
  • Mechanics
  • Medical Personnel
  • Modulus Of Elasticity
  • Skin Cancer
  • Stiffness
  • Three Dimensional
  • Two Dimensional
  • X-Ray Computed Tomography

Fields of Study

  • Physics

Readers

  • Medical Imaging.
  • Oncology and Biomarker-Based Cancer Detection.
  • Systems Analysis and Design