Short-Term Exercise and Prostate Cancer Prevention in African American Men

Abstract

This study seeks to examine the impact of exercise on serum factors related to prostate cancer in African-American men. Aims and Objectives: I. To recruit 40 African-American men between the ages of 40 and 70 who are at increased risk for developing prostate cancer and randomize them into an exercise intervention or control group. 2. To examine the effect of 12 days of aerobic exercise over 4 weeks on PSA levels in African-American men who have PSA levels under 4.0 ng/ml. 3. To examine the effect of 12 days of aerobic exercise on free and total testosterone insulin IGFI and SHBG levels in African-American men. A total of 40 African-American men between the ages of 40 - 70 yrs from the Howard University Cancer Center prostate screening program that have a PSA under 4.0 ng/ml a BMI > 25 and <35 kg/m2 <375 pounds and have been sedentary for at least 6 months (not exercising for more than 20 minutes 2 days a week). The men will be randomized into 2 groups 12 days of aerobic exercise (20 participants) or a control group (20 participants). The 12 days of exercise will consist of 30 minutes of walking on a treadmill at 50 - 60% of maximal heart rate reserve (HRR). Free testosterone lipids glucose insulin SHBG psychosocial measures body weight BMl and body fat anthropometric measurements height and weight will be measured before and after the study.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2007
Accession Number
ADA468516

Entities

People

  • Teletia R. Taylor

Organizations

  • Howard University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • African Americans
  • Biomedical Research
  • Body Weight
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Department Of Defense
  • Diseases And Disorders
  • Growth Factors
  • Health Services
  • Heart Rate
  • Hypertension
  • Medical Personnel
  • Neoplasms
  • Physicians
  • Prostate
  • Prostate Cancer
  • Testosterone

Fields of Study

  • Education

Readers

  • Exercise and Sports Science.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.