Posttreatment Changes in Escherichia coli Antimicrobial Susceptibility Rates Among Diarrheic Patients Treated with Ciprofloxacin

Abstract

Changes in antimicrobial resistance of Escherichia coli among deployed U.S. military personnel being treated for diarrhea were evaluated. Stool samples were collected pretreatment and on days 7, 14, and 28 posttreatment. Resistance to ciprofloxacin was noted in 13.3% of baseline specimens, and rates of resistance against multiple antibiotics increased dramatically from baseline to day 7 and then tapered off to return to pretreatment levels by day 28, except for ciprofloxacin, suggesting that population accumulative usage of fluoroquinolones may result in an incremental increase in resistance rates.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2005
Accession Number
ADA468892

Entities

People

  • David R. Rockabrand
  • David R. Tribble
  • John W. Sanders
  • Mark S. Riddle
  • Patrick J. Rozmajzl
  • Robert W Frenck
  • Shannon D. Putnam

Organizations

  • United States Naval Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Biomedical Research
  • Chemotherapy
  • Department Of Defense
  • Diarrhea
  • Electronic Mail
  • Escherichia
  • Escherichia Coli
  • Gastrointestinal Tract
  • Institutional Review Board
  • Microbiology
  • Microorganisms
  • Military Personnel
  • Navy
  • Resistance

Readers

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  • Microbial Pathology