Cell-surface Alpha-glucan in Campylobacter jejuni 81-176

Abstract

Campylobacter jejuni infection is a main source of severe gastroenteritis-related illnesses in humans and there is also evidence that it may be linked to neurological disorders. C. jejuni 81-176 is a virulent strain that has become the global model in the study of mechanisms and pathogenesis of C. jejuni infection. For this reason, we were engaged in studying the ne structures of cellsurface carbohydrate antigens of C. jejuni 81-176, namely, the capsule polysaccharide (CPS) and lipooligosaccharide (LOS). Serologically, C. jejuni 81-176 has been classified as belonging to serogroups HS23 and HS36, and indeed previous studies have shown that the LOS and CPS structures possess components similar to those expressed by serostrains HS23 and HS36. Here, we describe that in addition to the LOS and CPS, this strain also produced an independent cell-surface (1!4)-a-glucan capsule.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 14, 2005
Accession Number
ADA469117

Entities

People

  • Erzsebet Papp-szabo
  • Margaret I. Kanipes
  • Mario A. Monteiro
  • Patricia Guerry

Organizations

  • University of Guelph

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Carbohydrates
  • Chemical Shifts
  • Chemical Synthesis
  • Chemistry
  • Chitin
  • Diseases And Disorders
  • Guillain-Barre Syndrome
  • Infection
  • Magnetic Resonance
  • Materials
  • Nuclear Magnetic Resonance
  • Organic Chemistry
  • Polysaccharides
  • Resonance
  • Sugars
  • Wound Infections

Readers

  • Immunology
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Microbial Pathology