Tool Integration Framework for Bio-Informatics

Abstract

Experience in developing tool integration solutions for engineer domains indicates that the key ingredient for robust tool integration is semantically precise definition of interchange format. The project described in this report developed a robust, scalable, extensible, and standards-based tool integration framework for systems biology applications. Model-based techniques were developed and applied to formally and precisely define the interchange formats using metamodels and semantic well-formedness rules. These interchange formats were used for integrating diverse systems biology computational tools. The report describes the tool integration framework, interchange formats, and applications to representative systems biology workflows.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2007
Accession Number
ADA469991

Entities

People

  • Sandeep Neema

Organizations

  • Vanderbilt University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force Research Laboratories
  • Computational Biology
  • Computational Complexity
  • Computational Science
  • Computer Programming
  • Computer Programs
  • Data Sets
  • Debugging
  • Engineering
  • Equations
  • Fish
  • Kalman Filters
  • Language
  • Mathematical Models
  • Standards
  • Systems Biology
  • Systems Engineering

Fields of Study

  • Computer science

Readers

  • Computational Linguistics
  • Distributed Systems and Data Platform Development
  • Software Engineering.