Accumulation of Large Amounts of Hyperpolarized Xe-129 & Applications to Xe-129 Spectroscopy

Abstract

We have studied the physics underlying the production, accumulation, and cryogenic separation of hyperpolarized xenon-129. This research has led to a dramatically improved understanding of the physics behind nuclear relaxation in solid xenon and resolved long-standing discrepancies between theoretical predictions and experimental observation. The information gained from these experiments allowed us to produce greater quantities of hyperpolarized 129Xe with higher nuclear polarization. This in turn permitted us to begin cutting-edge studies applying hyperpolarized 129Xe nuclear magnetic resonance (NMR) spectroscopy to samples of biological interest. Specifically, we performed preliminary experiments which demonstrated that hyperpolarized 129Xe spectroscopy may be useful in the diagnosis of atherosclerosis.

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Document Details

Document Type
Technical Report
Publication Date
Jan 15, 2007
Accession Number
ADA470040

Entities

People

  • William Happer

Organizations

  • Princeton University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Alkali Metals
  • Chemical Shifts
  • Crystal Lattices
  • Detection
  • High Resolution
  • Magnetic Fields
  • Magnetic Resonance
  • Materials
  • Nuclear Magnetic Resonance
  • Nuclear Spins
  • Phase Transformations
  • Polarization
  • Quantum Properties
  • Resonance
  • Spectroscopy
  • Vascular Diseases

Fields of Study

  • Physics

Readers

  • Medical Imaging.
  • Molecular Photonics/Laser Physics
  • Theoretical Analysis.