Selenium Potentiates Chemotherapeutic Selectivity: Improving Efficacy and Reducing Toxicity
Abstract
The goal of the research is to evaluate the contribution of DNA repair to the protective effects of selenium in the context of chemotherapy. Specifically, the aims are to determine whether selenium-induced protection from DNA-damaging chemotherapeutics in vivo corresponds to reduced myelosuppression. Second, determine if selenium induced protection from chemotherapeutic toxicity corresponds to elevated DNA repair in vivo.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2007
- Accession Number
- ADA470578
Entities
People
- Joshua L. Fisher
Organizations
- Indiana University Bloomington