Enzymatic Decontamination of Environmental Organophosphorus Compounds
Abstract
This final report describes the research performed during the award period (June 5, 2003 to December 4, 2006). The main thrust of the research project was to investigate the surface chemistry of and molecular interactions between OP compounds and enzymes. The objective were: i) to characterize the Langmuir films of organophosphorus acid hydrolase (OPH) and organophosphorus acid anhydrase (OPAA) by studying their interfacial and spectroscopic properties at air/water interface; ii) to investigate the molecular interactions between OPH and OPAA and the OP compounds using Polarization Modulation FTIR spectroscopy; iii) to characterize the topography of OPH and OPAA by scanning probe and environmental scanning electron microscopies; iv) to characterize the basic features of AChE biosensor based on LB film technology. v) to simulate the active site of acetylcholinesterase (AChE)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 04, 2006
- Accession Number
- ADA470792
Entities
People
- Roger M. Leblanc
Organizations
- University of Miami