A Problem-Solving Environment for Biological Network Informatics: Bio-Spice

Abstract

The integration of multiple bioinformatics tools into an integrated suite poses many software engineering, social, and research challenges. We present our work on Bio-SPICE, an integrated open-source framework of tools for modern biology. SRI led the integration tasks, bringing together a community of researchers and practitioners to agree on a set of standards and practices that enabled multiple tools from multiple institutions to be brought to bear on problems of interest to biologists working on DoD-relevant problems. Working through communication and cultural barriers, the Bio-SPICE community developed good working relationships and built a series of impressive use cases, highlighting the effectiveness of combinations of computational tools from multiple sources working together on a common problem. This report documents the efforts at SRI International in leading the integration and combining research efforts across the Bio-SPICE program, including the development of the Bio-SPICE user interface, standards, and community working groups.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2007
Accession Number
ADA471395

Entities

People

  • Charles J. Pedersen
  • Patrick Lincoln

Organizations

  • SRI International

Tags

Communities of Interest

  • Cyber
  • Energy and Power Technologies
  • Engineered Resilient Systems

DTIC Thesaurus Topics

  • Computational Biology
  • Computational Fluid Dynamics
  • Computational Science
  • Computer Programming
  • Computers
  • Data Mining
  • Database Management Systems
  • Databases
  • Engineers
  • Information Science
  • Mathematical Models
  • Network Science
  • Relational Databases
  • Software Development
  • Systems Biology
  • Teamwork
  • Two Dimensional

Fields of Study

  • Computer science

Readers

  • Academic Conference Management
  • Distributed Systems and Data Platform Development
  • Wave Propagation and Nonlinear Chaotic Dynamics.