How Ebola and Marburg Viruses Battle the Immune System

Abstract

The filoviruses Ebola and Marburg have emerged in the past decade from relative obscurity to serve now as archetypes for some of the more intriguing and daunting challenges posed by such agents. Public imagination is captured by deadly outbreaks of these viruses and reinforced by the specter of bioterrorism. As research on these agents has accelerated, it has been found increasingly that filoviruses use a combination of familiar and apparently new ways to baffle and battle the immune system. Filoviruses have provided thereby a new lens through which to examine the immune system itself.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2007
Accession Number
ADA471860

Entities

People

  • Alan L. Schmaljohn
  • Lieping Chen
  • Mansour Mohamadzadeh

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Adaptive Immunity
  • Animal Diseases
  • Antiviral Agents
  • Blood
  • Cell Physiological Processes
  • Cells
  • Epithelial Cells
  • Equine Encephalitis
  • Hemorrhage
  • Interferon
  • Lymphocytes
  • Proteins
  • Vaccines
  • Viral Structures
  • Virion
  • Virus Diseases
  • Viruses

Fields of Study

  • Biology

Readers

  • Educational Psychology
  • Infectious Disease/Epidemiology
  • Systems Analysis and Design