Radiation Biomarker Research Using Mass Spectrometry

Abstract

Using mass spectrometry to investigate biomarkers from radiation exposure is fairly new. The implementation of mass spectrometric techniques to systems of biological interest has only recently taken off. Therefore, there have only been a limited number of applications of mass spectrometry in radiation dosimetry research. This review is intended to give an overview of mass spectrometry and its application to biological systems and biomarker discovery and how that might relate to relevant radiation dosimetry studies and how these two areas might be combined to benefit both areas of research. Efficient proteomics analyses have necessitated the use of various methods of mass spectrometry in recent years; especially concerning biomarker detection and characterization. A brief summary of the research thus far conducted follows.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2007
Accession Number
ADA473187

Entities

People

  • Stephan B. Bach
  • Walter Hubert

Organizations

  • University of Texas at San Antonio

Tags

DTIC Thesaurus Topics

  • Air Force Research Laboratories
  • Blood
  • Chemical Synthesis
  • Chemistry
  • Detection
  • Diseases And Disorders
  • Liquid Chromatography
  • Mass Spectrometry
  • Medical Personnel
  • Proteins
  • Proteomics
  • Radiation
  • Radio Frequency
  • Salivary Glands
  • Spectrometry
  • Standards
  • Two Dimensional

Fields of Study

  • Chemistry

Readers

  • Nuclear and Radiation Engineering.
  • Oncology and Biomarker-Based Cancer Detection.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology