Expression and Genomic Profiling of Minute Breast Cancer Samples. Addendum

Abstract

Genetic and gene expression profiling based diagnosis promises to refine (1) and potentially revolutionize (2) the existing cancer staging system and the management of early disease. Microarray-based gene expression profiling and Array-based Comparative Genomic Hybridization (array-CGH) offers global views of cancer genomes and transcriptomes by detecting amplification or deletion of cancer genes (3-10), whereas techniques like real time PCR (11) can be used for validation and quantification of the identified genomic changes.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2007
Accession Number
ADA473876

Entities

People

  • G. M. Makrigiorgos

Organizations

  • Dana–Farber Cancer Institute

Tags

DTIC Thesaurus Topics

  • Breast Cancer
  • Cell Line
  • Cells
  • Chemical Reactions
  • Computational Science
  • Data Analysis
  • Department Of Defense
  • Dna Microarrays
  • Gene Expression
  • Genetics
  • Health Services
  • Materials
  • Medical Personnel
  • Neoplasms
  • New England
  • Oncology
  • Polymerase Chain Reaction

Fields of Study

  • Biology

Readers

  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology