Near Infrared Spectroscopy for Improving Breast Core Needle Biopsy
Abstract
The objective of the proposed research is to develop a device to reduce the frequency of breast re-excision surgery in patients with breast malignancies. The purpose of Task 1 was to design a spectral imaging system that will provide two-dimensional measurements approximately 0.5-2.0 mm within breast tissues. Monte Carlo simulations determined that the spacing between each imaging channel should be at least 10mm to have an SNR greater than 100. The monochromator slit size and channel spacing determined that there could be 25,600 um illumination fibers and 25 channels. Four collection fibers per channel was optimal to be certain that all fibers could be imaged on the CCD without any cross-talk between signals. The purpose of Task 2 was to build a fiber optic probe with two imaging channels rather than the entire imaging probe to test the conceptual design. The two-channel probe has been built in our laboratory using 4, 200 micron collection fibers and 1, 600 micron illumination fiber in each channel.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2007
- Accession Number
- ADA475506
Entities
People
- Torrev M. Bydlon
Organizations
- Duke University