Optimization and Comparison of Different Digital Mammographic Tomosynthesis Reconstruction Methods

Abstract

Digital breast tomosynthesis is a three-dimensional imaging technique with limited-angle series of projection images that allows the reconstruction of depth information along the breast. This study investigated optimized and compared different tomosynthesis methods and chose the optimal one for breast tomosynthesis imaging. We investigated several 3-D tomosynthesis reconstruction algorithms and studied the effect of acquisition parameters for different candidate reconstruction algorithms according to computer simulation and physical measurements of impulse response analysis modulation transfer function and noise power spectrum. We applied a relative noise-equivalent quanta (NEQ) analysis to compare candidate algorithms and acquisition parameters. Additionally the importance of point-by-point back projection (BP) for isocentric motion in breast tomosynthesis was investigated. It improves the in-plane sharpness of structures such as microcalcifications which bear important meaning in clinical tasks for breast cancer detection.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2008
Accession Number
ADA475536

Entities

People

  • James T. Dobbins Iii
  • Ying Chen

Organizations

  • Duke University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Algorithms
  • Biomedical Engineering
  • Breast Cancer
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Geometry
  • Imaging Techniques
  • Power Spectra
  • Simulations
  • Three Dimensional
  • Tomography
  • Tomosynthesis
  • Transfer Functions
  • Two Dimensional
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Image Processing and Computer Vision.
  • Oncology and Biomarker-Based Cancer Detection.