Incontinentia Pigmenti

Abstract

Incontinentia pigmenti is an X-linked dominant disorder with characteristic skin lesions and anomalies of teeth, hair, nails, eyes, and central nervous system. Cutaneous lesions are the most common identifiable abnormality and characterized in 4 stages. ONS abnormalities are the cause of most morbidity in this disorder. The NEMO gene is identified with this disorder. In this update, Drs. David Hsieh and Bhagwan Moorjani from Children's National Medical Center in Washington, DC highlight the reporting of reversible brain lesions by MRI, and the addition of the gothic palate in the spectrum of oral and dental anomalies in incontinentia pigmenti.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2008
Accession Number
ADA478060

Entities

People

  • Bhagwan Moorjani
  • David T. Hsieh

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Brain
  • Cardiovascular Physiological Phenomena
  • Chromosomes
  • Congenital Abnormalities
  • Eye Diseases
  • Genetics
  • Health Services
  • Medical Personnel
  • Retinal Diseases
  • Skin Diseases

Fields of Study

  • Medicine

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