Reduction of Racial Disparities in Prostate Cancer

Abstract

Prostate inflammation or infection may increase the risk of prostate cancer. As antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat prostatitis and urinary tract infections (UTIs) our objective was to assess whether their use decreases the risk of prostate cancer. We conducted a case-control study among men with incident prostate cancer (N=65 cases) and without prostate cancer (N=195 controls) at the San Francisco Veteran Affairs medical center (VAMC) between June 1996 and June 2006. Neither total antibiotic use nor total anti-inflammatory use reduces the risk of prostate cancer (P >0.05). Our analysis did not reveal a relation between use of antibiotics or NSAIDs and the risk of prostate cancer but the width of the confidence intervals does not rule out a strong protective effect. A larger sample size is needed to determine whether antibiotics or NSAIDs use decreases the risk of prostate cancer.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2007
Accession Number
ADA478285

Entities

People

  • Nicholas Daniels

Organizations

  • University of California Regents

Tags

DTIC Thesaurus Topics

  • Age Groups
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Breast Cancer
  • Health
  • Health Care
  • Health Services
  • Infection
  • Intervals
  • Neoplasms
  • Pharmacies
  • Prostate
  • Prostate Cancer
  • Sexually Transmitted Diseases
  • Urinary Tract
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Microbial Pathology
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