Deregulated Wnt Signaling in Prostate Cancer

Abstract

The PCRP Prostate Cancer Training Award has supported my training for the past 12 months. During this time, I have continued to work towards attaining a better understanding of (a) the biology of prostate cancer, (b) the biology of the Wnt/beta-catenin signaling pathway, (c) the principle and application of cutting edge techniques in modern molecular and cellular biology, and (d) the principle and application of genetically engineered mouse (GEM) models, with the intent of becoming uniquely positioned to investigate the role of Wnt/beta-catenin signaling in the initiation, progression and metastasis of spontaneous autochthonous prostate cancer and the emergence of the androgen depletion independent phenotype. In addition to this rigorous technical training, I have continued to attend weekly lab meetings, division wide Cancer Biology Seminar series, and the Pacific Northwest SPORE in Prostate Cancer meetings. In addition, I attended the PCRP's Innovative Minds in Prostate Cancer Today (IMPaCT) meeting in Atlanta, Georgia.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2008
Accession Number
ADA478660

Entities

People

  • Scott Houghtaling

Organizations

  • Fred Hutchinson Cancer Center

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Androgens
  • Biology
  • Biomedical Research
  • Cancer
  • Cells
  • Culture Techniques
  • Diseases And Disorders
  • Epithelial Cells
  • Genetics
  • Metastasis
  • Neoplasms
  • Phenotypes
  • Prostate
  • Prostate Cancer
  • Tissues
  • Training

Fields of Study

  • Biology

Readers

  • Oncology
  • Oncology (Cancer Research).
  • Research Science/Academic Research

Technology Areas

  • Biotechnology