Tularemia: Current Diagnosis and Treatment Options

Abstract

Tularemia is an infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. Limitations in both culture and serologic testing have led to substantial research into new diagnostic techniques and their clinical application, with PCR testing as the best example. This review focuses on the utility of culture, PCR and serologic testing for tularemia. In addition, we also review the evidence to support different therapeutic options for tularemia, highlighting both the most effective supporting evidence for therapeutic recommendations as well as gaps in current knowledge. We conclude the article with suggestions regarding potential areas for future research.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2008
Accession Number
ADA480022

Entities

People

  • Andrew J. Simpson
  • Matthew J. Hepburn

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Blood
  • Cells
  • Diseases And Disorders
  • Immune Serums
  • Infection
  • Infectious Diseases
  • Lymphatic System
  • Lymphocytes
  • Medical Personnel
  • Microbiology
  • Microorganisms
  • Pcr Testing
  • Polymerase Chain Reaction
  • Rodents

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Systems Analysis and Design