Continuous Renal Replacement Therapy Improves Survival in Severely Burned Military Casualties With Acute Kidney Injury
Abstract
Background: Acute kidney injury in severely burned patients is associated with high mortality. We wondered whether early use of continuous renal replacement therapy (CRRT) changes outcomes in severely burned military casualties with predetermined criteria for acute kidney injury. Methods: Between November 2005 and June 2007, casualties admitted to our burn intensive care unit after sustaining burns in Iraq and Afghanistan, who subsequently developed acute kidney injury or circulatory shock or both, underwent CRRT. Baseline demographic, laboratory, and hemodynamic parameters were recorded. Both 28-day mortality and in-hospital mortality were evaluated and compared with a consecutive group of burn casualties with greater than 40% total body surface area (TBSA) burns, acute kidney injury, or nephrology consultation in the 2 years before the existence of our CRRT program. Conclusion: Aggressive application of CRRT in severely burned casualties with kidney injury significantly improves survival.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2007
- Accession Number
- ADA480328
Entities
People
- Christopher E. White
- David J. Barillo
- Elizabeth E. Mann
- Evan M. Renz
- Harcourt P. Edgecombe
- John A. Jones
- Kevin K Chung
- Luis A. Juncos
- Richard A. Clark
- Steven Wolf
Organizations
- United States Army Institute of Surgical Research