A Phase 1/2 Trial of a Tetravalent Live-Attenuated Dengue Vaccine in Flavivirus-Naive Thai Infants

Abstract

The Walter Reed Army Institute of Research (WRAIR) has produced a tetravalent live-attenuated dengue vaccine that has been well tolerated and immunogenic in U.S. adults and Thai children. As infants are considered by many as an important age group for vaccination in dengue-endemic countries, we evaluated the vaccine in Thai flavivirus-na ve infants who are at risk for dengue.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2006
Accession Number
ADA481707

Entities

People

  • A. Kerdpanich
  • A. Nisalak
  • B. L. Innis
  • C. Aree
  • D. W. Vaughn
  • K. H. Eckels
  • K. Tanakijaru
  • M. P. Mammen
  • R. J. Jarman
  • R. Putnak
  • R. Samakoses
  • R. V. Gibbons
  • S. Chunsuttiwat
  • S. Hengprasert
  • S. Simasathien
  • S. Thomas
  • T. P. Endy
  • V. Watanaveeradej
  • Weiqin Sun
  • Y. Hutagalung

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Blood
  • Dengue
  • Diseases And Disorders
  • Health
  • Health Care
  • Health Services
  • Hospitals
  • Immunogenicity
  • Medical Personnel
  • Pain
  • Proteins
  • Public Health
  • Vaccination
  • Vaccines
  • Virus Diseases
  • Viruses

Readers

  • Infectious Disease/Epidemiology
  • Vector-Borne Disease and Entomology

Technology Areas

  • Biotechnology