Biodegradable Poly (Ester Urethane) Urea Biomaterials For Applications in Combat Casualty Care

Abstract

A family of biocompatible, biodegradable poly(ester urethane)urea (PEUUR) biomaterials has been developed that degrade to non-toxic by-products and support the attachment and proliferation of cells. These two component materials are synthesized by reactive liquid molding, thus rendering them suitable for injection or casting into molds to form a desired shape. The clinical goal is to develop biologically active cast and injectable PEUUR biomaterials that promote bone wound healing and decrease the incidence of nonunions and infection.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2006
Accession Number
ADA481817

Entities

People

  • A. Sriniwasan
  • J. O. Hollinger
  • S. A. Guelcher

Organizations

  • Vanderbilt University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Attachment
  • Bacteria
  • Biomaterials
  • Biomedical And Dental Materials
  • Bone Fractures
  • Culture Techniques
  • Degradation
  • Engineering
  • Esters
  • Health Services
  • Hospitals
  • Infection
  • Materials
  • Polymer Degradation
  • Polymers
  • Resins

Fields of Study

  • Materials science

Readers

  • Nanocomposite Materials Science
  • Reinforced Composite Materials
  • Trauma Surgery or Emergency Medicine.