Synthetic Biomimetic Fluorophores for Micro/Nanosensor
Abstract
Proteins common in nature provide a rich source of potential fluorophores that can be used as taggent materials. Many of these fluorophores have been demonstrated to be effective molecular probes (e.g., green fluorescent protein (GFP)). The objective of this research is to find, isolate, sequence, and synthetically produce (from a natural source) synthetic fluorophores extracted from reef coral or rcGFP. From this investigation we discovered two novel clones with unique sequences for rcGFP and rcCFP. This research provided a better understanding of rcGFP's suitability for incorporation into micro or nano-sensory devices. Once synthetically created, these fluorophores are meant for design as triggering and signaling devices. These optical switches will possess far greater environmental stability and survivability than their natural analogs. Micro and nano-sensory devices are envisioned as helping the soldier to better understand the battlespace environment by providing remotely sensed, geospatial awareness.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 2006
- Accession Number
- ADA481868
Entities
People
- C. B. Smith
- J. E. Anderson
- P. M. Gillevet
Organizations
- Engineer Research and Development Center