Detection and Decontamination Kinetics of Vx and Related Compounds by LC/MS
Abstract
Liquid Chromatography/Mass Spectrometry (LC/MS) and Nuclear Magnetic Resonance Spectrometry (NMR) analytical methods were tested for the detection of EA-2192 in caustic monoethanolamine (MEA) decontamination solution. Precision and accuracy testing was done for the LC/MS method which gave a minimum detection limit (MDL) of 7.6 ng/mL after dilution, or 760 ng/mL in the original solution, which was adequate for the study and gave better sensitivity than NMR. The spike recovery was 70%. The method was used to measure the kinetics of VX and EA-2192 reaction at temperatures of 25 and 50 C. Half life of VX in the solution at 50 C was 5 min. or less, but the half life of EA-2192 was 56 min. For runs at room temperature, the decrease in the EA-2192 concentration was much slower. Results from NMR analyses were in good agreement.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2003
- Accession Number
- ADA483068
Entities
People
- David J. Mcgarvey
- H. D. Durst
- Richard J. O'connor
- William Creasy