A Dendritic Model of Coincidence Detection in the Avian Brainstem
Abstract
The coincidence detector neurons in the auditory brainstem detect interaural time differences (ITDs). Inspired by a minimal biophysical model [Agmon-Snir et al, Nature 393, 268-272 (1998)], we constructed a model using the NEURON environment. ITD coding was improved when the inputs from both ears were located on the bipolar dendrites and segregated over having both inputs on the soma. Thus the model behaves both like the in vivo coincidence detectors and the minimal model. The model has enabled us to explore features of the coincidence detector neurons unexplained by the simple biophysical model, including the effect of synapse location and multiple dendrites.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1998
- Accession Number
- ADA483451
Entities
People
- Catherine E. Carr
- Jonathan Z. Simon
- Shihab A. Shamma
Organizations
- University of Maryland