Development of Microdevices for Biomolecular Detection

Abstract

Biosensors suitable for providing informed rapid treatment analysis for soldiers and real-time environmental monitoring of toxic agents were developed. In particular, glass encapsulated field-effect sensors that are chemically robust and batch-fabricated by a conventional 6" wafer process were developed and demonstrated for the following applications: (i) Polymerase Chain Reaction (PCR) product quantification, (ii) Integrated microelectronic device for label-free nucleic acid amplification and detection, and (iii) Monitoring of heparin and its low molecular weight analogs.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2008
Accession Number
ADA484233

Entities

People

  • Scott Manalis

Organizations

  • Massachusetts Institute of Technology

Tags

Communities of Interest

  • Advanced Electronics
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Anticoagulants
  • Biological Sciences
  • Biotechnology
  • Chain Reactions
  • Chemical Reactions
  • Chemical Synthesis
  • Chemistry
  • Detection
  • Detectors
  • Environmental Monitoring
  • Measurement
  • Molecular Weight
  • Monitoring
  • Nucleic Acids
  • Optical Detection
  • Polymerase Chain Reaction
  • Standards

Fields of Study

  • Chemistry

Readers

  • Integrated Circuit Design and Technology.
  • Molecular Genetics
  • Molecular and Cellular Biochemistry

Technology Areas

  • Biotechnology
  • Microelectronics
  • Microelectronics - Microelectromechanical Systems