Development of Methods for the Real-Time and Rapid Identification and Detection of TSE in Living Animals Using Fluorescence Spectroscopy of the Eye

Abstract

Year three of the project the current reporting period, has shown considerable progress. Our preliminary investigations so far suggest that the most promising part of the eye for revealing spectroscopic signatures of neurological disease is the retina. Our experiments have so far been limited to sheep. Our experiments have been designed to address the following questions: (1) Can ocular spectra be diagnostic of neurological disease? (2) Can the effects of neurological disease be separated from those associated with normal aging? (3) Can images of the eye be obtained that report on neurological disease? Our results indicate that we can answer all three questions in the affirmative.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2006
Accession Number
ADA484867

Entities

People

  • Jacob W. Petrich

Organizations

  • Iowa State University

Tags

DTIC Thesaurus Topics

  • Biological Pigments
  • Central Nervous System
  • Chemistry
  • Data Sets
  • Detection
  • Diseases And Disorders
  • Identification
  • Images
  • Lipofuscin
  • Materials
  • Nervous System
  • Optic Nerve
  • Retinal Diseases
  • Spectra
  • Spectroscopy
  • Spinal Cord
  • Steady State

Readers

  • Neuroscience
  • Virology (or Medical Virology).
  • Vision Science/Vision Psychology/Cognitive Neuroscience.