Concurrent MR-NIR Imaging for Breast Cancer Diagnosis

Abstract

The primary objective of this research program is to investigate concurrent near infrared (NIR) optical and magnetic resonance (MR) imaging for breast cancer diagnosis. The NIR diffuse optical imaging offers novel criteria for cancer differentiation with the ability to measure (in vivo) oxygenation and vascularization state, the uptake and release of contrast agents and chromophore concentrations with high sensitivity. However, NIR diffuse optical tomography is inherently a low spatial resolution imaging modality due to diffuse nature of light photons. Alternatively, MRI provides high spatial resolution with excellent tissue discrimination, but has limited ability to monitor hemoglobin dynamics and other contrast mechanisms that optical imaging provides. Therefore, concurrent MRI-NIR optical imaging brings together the most advantageous aspects of the two imaging modalities for breast cancer diagnosis.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2008
Accession Number
ADA488046

Entities

People

  • Birsen Yazıcı

Organizations

  • Rensselaer Polytechnic Institute

Tags

Communities of Interest

  • Advanced Electronics
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Breast Cancer
  • Cancer
  • Computational Complexity
  • Computational Science
  • Detection
  • Detectors
  • Health Services
  • Imaging Techniques
  • Information Science
  • Kalman Filters
  • Magnetic Resonance
  • Oxygenation
  • Statistical Analysis
  • Supervised Machine Learning
  • Three Dimensional
  • Tomography
  • Two Dimensional

Fields of Study

  • Physics

Readers

  • Medical Imaging.