Site-Specific Differentiation of Fibroblasts in Normal and Scleroderma Skin

Abstract

The results from year I of funding suggest that appropriate markers and technologies are in place for systematic investigation of the positional identity of fibroblasts both in normal and diseased tissues. Because long noncoding RNAs are the predominant position specific output of the HOX loci they may constitute excellent markers for testing the idea that scleroderma involves altered fibroblast positional identity.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2008
Accession Number
ADA488076

Entities

People

  • Howard Y. Chang

Organizations

  • Stanford University

Tags

DTIC Thesaurus Topics

  • Animal Structures
  • Cells
  • Chromosomes
  • Computational Biology
  • Computer Programming
  • Coordinate Systems
  • Dna Microarrays
  • Epidermis
  • Epithelial Cells
  • Gene Expression
  • Genetics
  • Identities
  • Proteins
  • Skin Cancer
  • Skin Diseases
  • Stem Cells
  • Systems Biology

Readers

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