Epidermal Laser Stimulation of Action Potentials in the Frog Sciatic Nerve

Abstract

Measurements of laser stimulated action potentials in the sciatic nerve of leopard frogs (Rana pipiens) were made using two infrared lasers. The dorsal sides of the frog's hind limbs were exposed to short-pulsed 1540 nm and 1064 nm wavelengths at three separate spot sizes: 2 mm, 3 mm, and 4 mm. Energy density thresholds were determined for eliciting an action potential at each experimental condition. Results from these exposures showed similar evoked potential thresholds for both wavelengths. The 2-mm diameter spot sizes yielded action potentials at irradiance levels almost double that seen with the larger beam sizes.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2008
Accession Number
ADA492590

Entities

People

  • Douglas N. Goddard
  • Michelle L. Imholte
  • Nichole M. Jindra
  • Robert J. Thomas

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Contracts
  • Diameters
  • Directed Energy Weapons
  • Governments
  • Infrared Lasers
  • Laser Beams
  • Laser Safety
  • Lasers
  • Measurement
  • Nerves
  • Nervous System
  • Peripheral Nervous System
  • Radiation
  • Sciatic Nerve
  • Yag Lasers

Fields of Study

  • Physics

Readers

  • Aquatic Ecology
  • Optical Physics and Photonics.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Directed Energy
  • Directed Energy - Lasers