Development of Methods for the Real-Time and Rapid Identification and Detection of TSE in Living Animals Using Fluorescence Spectroscopy of the Eye

Abstract

Our investigations continue to suggest that the most promising part of the eye for revealing spectroscopic signatures of neurological disease is the retina. Our experiments have so far been limited to sheep. Our experiments have been designed to address the following questions: 1. Can ocular spectra be diagnostic of neurological disease? 2. Can the effects of neurological disease be separated from those associated with normal aging? 3. Can images of the eye be obtained that report on neurological disease? Our results indicate that we can answer all three questions in the affirmative. Enormous progress has been made since the inception of this work. We are continuing to search funding for its continuation and are currently implementing methods to make the scanning process more rapid.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2007
Accession Number
ADA493421

Entities

People

  • Jacob W. Petrich

Organizations

  • Iowa State University

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Central Nervous System
  • Chemical Properties
  • Chemistry
  • Contamination
  • Department Of Defense
  • Detection
  • Fluorescence
  • Food Chains
  • Information Operations
  • Lipofuscin
  • Nervous System
  • Optic Nerve
  • Spectra
  • Spectroscopy
  • Spinal Cord
  • Tissues

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Systems Analysis and Design
  • Vision Science/Vision Psychology/Cognitive Neuroscience.