Geographical Distribution of Genotypic and Phenotypic Markers Among Bacillus Anthracis Isolates and Related Species by Historical Movement and Horizontal Transfer

Abstract

The geographical distribution of Bacillus anthracis strains and isolates bearing some of the same genetic markers as the Amerithrax Ames isolate was examined and evaluated. At least one mechanism for the horizontal movement of genetic markers was shown amongst isolates and closely related species and the effect of such mixing was demonstrated on phenotype. The results provided potential mechanisms by which attempts to attribute isolates of Bacillus anthracis to certain geographical and isolate sources may be disrupted.

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Document Details

Document Type
Technical Report
Publication Date
Jan 09, 2009
Accession Number
ADA494693

Entities

People

  • A. Delos Santos
  • C. J. Andrews
  • E. A. Holwitt
  • J. E. S. Parker
  • J. Kalns
  • J. L. Kiel
  • Mark T. Wade
  • R. P. Mccreary
  • W. D. Walker

Organizations

  • Air Force Research Laboratory

Tags

DTIC Thesaurus Topics

  • Biology
  • Blood
  • Chemical Reactions
  • Chemistry
  • Genes
  • Genetic Markers
  • Genetic Variation
  • Genetics
  • Genotypes
  • Infection
  • Mutations
  • Nucleotides
  • Polymerase Chain Reaction
  • Rodents
  • Sequences
  • Spot Tests
  • Vaccines

Fields of Study

  • Biology

Readers

  • Marine Mammal Biology
  • Microbial Pathology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology