Prostate Dose Escalation by a Innovative Inverse Planning-Driven IMRT

Abstract

The goal of this project is to develop innovative inverse planning techniques for prostate radiation therapy. In the last funding period significant progress has been made toward the goal of the project. In the past funding year, the PI group has continued to advance prostate radiation therapy techniques. A few important milestones have been achieved toward the goal of the project. These include: (i) Proposed a novel total-variation regularization based inverse planning technique for prostate IMRT; (ii) Applied compressed sensing concept to IMRT and IMAT inverse planning and established a multi-objective optimization framework; (iii) Developed a voxel-specific penalty scheme for TRV-based inverse planning; (iv) Established a cine-EPID image retrospective dose reconstruction in IMRT dose delivery for adaptive planning and IMRT dose verification. These works are both timely and important and should lead to widespread impact on prostate cancer management.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2008
Accession Number
ADA494754

Entities

People

  • Lei Xing

Organizations

  • Stanford University

Tags

Communities of Interest

  • Advanced Electronics
  • Air Platforms
  • Energy and Power Technologies
  • Engineered Resilient Systems
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Computational Science
  • Computer Vision
  • Detectors
  • Diagnostic Imaging
  • Health Services
  • Information Processing
  • Medical Personnel
  • Radiation Oncology
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Distributed Systems and Data Platform Development
  • Medical Imaging.