Analysis of Adverse Events after Anthrax Immunization in US Army Medical Personnel
Abstract
A broad range of health effects in a cohort of 601 health rare personnel, immunized with anthrax vaccine adsorbed (AVA) as a military occupational health requirement, were assessed to evaluate adverse events both qualitatively and quantitatively. Active surveillance showed that localized reactions were common and occurred more often in women than men. five patients were reported to the Vaccine Adverse Event Reporting System, hut only one event could he definitively attributed to immunization, a large localized reaction. Two separate cohort studies, one using nested data from a standardized health risk appraisal instrument and the other comparing rates of outpatient visits and hospilizations, did not reveal significant differences between AVA-immunized and unimmunized individuals. Our findings suggest that AVA is relatively reactogenic hut do not indicate serious adverse health effects due to immunization.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2003
- Accession Number
- ADA495915
Entities
People
- Glenn M. Wasserman
- John D. Grabenstein
- Lance G. Golder
- Linda Z. Wang
- Mark V Rubertone
- Paul P. Gibbs
- Phillip R. Pittman
Organizations
- Tripler Army Medical Center