Integration of Optical Protein and Quantum Dot Films for Biosensing
Abstract
The unique energy transfer interaction between the optical protein bacteriorhodopsin (bR) and Cd/Se quantum dots (QDs) provides a potential modulation mechanism for bio-nano electronic application. We have utilized ionic self-assembled monolayer (I-SAM) techniques to create a novel alternating monolayer system of QDs and bR on a conductive ITO substrate. Results demonstrate the ability to efficiently create bR/QD multilayer films along with the ability to control bR/QD spacing on the nanometer scale. I-SAM films of this nature demonstrate a sharp decrease in QD emission when deposited in close proximity to bR, suggesting possible fluorescence resonance energy transfer (FRET) effects in a bR/QD nanoscale system. The ability to modulate the QD photonic output based on proximity to bR in the I-SAM films could provide a direct method to modulate the electrical output for bio-nano sensing applications.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2008
- Accession Number
- ADA496244
Entities
People
- Craig Friedrich
- Donald Lueking
- Govind Mallick
- Mark H Griep
- Shashi P Karna
Organizations
- Michigan Technological University