The Potential Application of Hairless Guinea Pigs as a Replacement for the Yucatan Mini-pig in Animal Studies

Abstract

The Yucatan mini-pig (Sus scrofa) is one of the most widely used animal models for skin damage studies because it shares many of the same physical properties as human skin. While the Yucatan is ideal for laser exposure studies using a large spot size, its size and cost are excessive for projects using smaller beams. This experiment performed histological analysis of skin biopsies from pigmented Hairless Guinea Pigs (Cavia porcellus) for epidermal thickness and melanin distribution. That data was then compared to similar information on the Yucatan.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2009
Accession Number
ADA498510

Entities

People

  • Michelle Imholte
  • Nichole Jindra

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Alkanes
  • Animals
  • Blood
  • Cells
  • Department Of Defense
  • Directed Energy Weapons
  • Epidermis
  • Government Procurement
  • Governments
  • Laboratory Animals
  • Medical Personnel
  • Military Research
  • Motor Skills
  • Rodents
  • Thickness

Readers

  • Pulsed Power and Plasma Physics.
  • Toxicology/Environmental Toxicology
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Directed Energy