Novel Carbon Nitride Nanowire (CNW) Conjugates for Breast Cancer Treatment

Abstract

In this program we have tested the concept that carbon nitride nanowires (CNWs)-conjugated to Herceptin can selectively target and photo-thermally ablate HER2-positive breast cancer tissues using penetrating near infra-red radiation (1.06 microns). Our initial results in cell culture suggest that CNWs are far superior transducers of radiation to the SWNTs or Ag nanoshells due to their metallic nature and aspect ratio. Initial animal studies have begun.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2008
Accession Number
ADA501652

Entities

People

  • David L. Carroll

Organizations

  • Wake Forest University

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Breast Cancer
  • Carbon Nanotubes
  • Cell Physiological Processes
  • Chemical Vapor Deposition
  • Chemistry
  • Culture Techniques
  • Electromagnetic Radiation
  • Fullerenes
  • Heat Transfer
  • Materials
  • Materials Science
  • Nanomaterials
  • Nanowires
  • Near Infrared Radiation
  • Neoplasms
  • Radiation
  • Specific Heat

Fields of Study

  • Physics

Readers

  • Nanocomposite Materials Science
  • Oncology (Cancer Research).